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Essay / Risk Factors and Symptoms of Alzheimer's Disease , heart, liver and kidneys. Amyloid is an irregular protein structure produced by a person's bone marrow. Alzheimer's disease is the most common type of amyloidosis and is a progressive disease that impairs memory, as well as other important functions of the brain. The hippocampus, which plays an essential role in the formation of new memories, is affected in the early stages of Alzheimer's disease. Research has shown that the volume of the hippocampus is decreased by more than twenty percent in cases of patients with Alzheimer's disease. Alzheimer's disease is also the leading cause of dementia, a series of impairments that result in the loss of cognitive abilities. In frontotemporal dementia, the patient's eating habits are often disrupted, due to deterioration of the hypothalamus. Say no to plagiarism. Get a tailor-made essay on "Why violent video games should not be banned"? Get an original essay According to an article published in the Lancet on April 30, 2011, titled "The three stages of Alzheimer's disease", at the turn of This century, there will be 24 million people with dementia worldwide, the majority of whom will suffer from Alzheimer's disease. This number is expected to increase to more than 80 million over the next 20 years or so. Patients have difficulty remembering people's names and may also notice that they begin to forget the names of places or familiar objects more often than they might have previously. It is also very important to note that it is completely normal to forget the name of a receipt or run an errand from time to time, but if it begins to have a negative impact on daily life, it can be a sign of an underlying illness such as Alzheimer's disease or mild cognitive impairment. deficiency. They may start calling things by the wrong name or getting stuck and are often unaware that they called something by the wrong name after they have done so. Alzheimer's patients may also place objects in unusual places. For example, while unpacking groceries, a person may put toothpaste in the oven, but does not remember doing so until later and cannot find the item. Repetition is another important sign of Alzheimer's disease. A typical scenario may be that they ask the same question over and over again, because the person forgets that they already asked the particular question. They may ask what day it is several times throughout the day, without their knowledge. Confusion, increased anxiety, loss of self-confidence and fear are also very common in patients with early-stage Alzheimer's disease. Demonstrate poor judgment and difficulty making decisions in most, if not all, aspects of life. Neurophysiological damage to the frontal lobe, an area involved in reasoning and planning, has a causal role in these symptoms. Aimless wandering is another indicator of illness. They may also become confused in a well-known environment and wonder how they got there and why they are there. Bad mood and personality differences are also two main symptoms of Alzheimer's disease – neurophysiological changes in the amygdala are the cause. homework. Often, in Alzheimer's disease, tasksonce relatively easy for the patient, such as shopping or doing mental calculations, become increasingly laborious. Forgetting or confusing dates and times on a fairly regular basis and not remembering them until some time later, or perhaps not remembering them at all. their presence is also symptomatic of the disease. This impacts a person's daily life as they may forget to attend several appointments and family functions, and may also notice that they are making mistakes in their work. greatest challenges in interpreting language, both aurally and when reading. Difficulties with writing can also occur and agraphia is one of the first signs of Alzheimer's disease, along with spelling mistakes, written and spoken grammatical errors and a general decline in the ability to articulate. Studies have shown that testing writing skills is an appropriate way to assess the stage of dementia a patient may be at. Sleep Disturbances The pathophysiological effects of Alzheimer's disease on the brain are thought to alter the sleep/wake cycle. In the early stages of the disease, people with Alzheimer's disease may sleep excessively and often wake up feeling confused. In later stages of the disease, people with Alzheimer's sleep much less and at irregular intervals, often dozing during the day and night. Hallucinations: events characterized by the apparent perception of someone or something that is not actually there. . Their severity often increases as the patient's condition deteriorates. Patients, according to the Alzheimer's Society UK, often experience visuospatial difficulties such as difficulty navigating steps and maneuvering objects. At this intermediate stage, patients also show a decrease in their ability to concentrate on a series of tasks or to concentrate on a book or the script of a television show for example. The risk of Alzheimer's disease increases significantly after the age of 65, and a person's chance of developing dementia doubles every ten years after the age of 60. More than 30% of patients are over 85 years old. Early-onset Alzheimer's disease can also occur between the ages of 40 and 50. Additionally, medical research published by the Feinberg School of Medicine at Northwestern University in Chicago found an accumulation of amyloid protein deposits in the brains of some deceased young adults as young as 20 years old. Such a finding is highly indicative of the early or preclinical stages of Alzheimer's disease. Smoking is linked to a wide range of illnesses, particularly many forms of cancer and heart disease, as well as type 2 diabetes. Studies have also concluded that smokers are at a 40% higher risk of developing the disease. Alzheimer's than non-smokers and ex-smokers. Additionally, research has shown that former smokers can reduce their risk of developing Alzheimer's disease by quitting smoking. Diabetes Numerous medical studies have also established a very strong correlation between patients with type 2 diabetes and the risk of developing Alzheimer's disease later in life. Further research suggests that patients with type 2 diabetes are at twice the risk of developing Alzheimer's disease than those without type 2 diabetes. High cholesterol and hypertension have both been established as risks for the development of Alzheimer's disease, particularly vascular dementia, due to damage to the blood vasculature..
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