-
Essay / DNA and DNA profiling made simple - 3447
1.1. AmplificationIf the quantity of isolated DNA is not sufficient, the specialist increases it to an optimal level via an amplification technique using the polymerase chain reaction (PCR) process. Additionally, PCR targets specific locations on the DNA strand called loci (singular: locus) to produce similar copies.1.2. ElectrophoresisIn this process, the specialist separates materials based on their size and composition of DNA strands on a particular gel in the presence of electricity. The figure below displays the electrophoresis results (courtesy of How Stuff Works).1.3. AnalysisThe final step is to analyze the DNA screening results obtained based on a particular program of the National DNA Database. Short tandem repeat (STR) analysis dominates the process for criminal investigations. Indeed, STRs do not characterize the physical appearance of an individual. The field of forensic medicine emphasizes the use of STR because its locus is composed of two alleles.2. IntroductionThe evolution of technology brings unlimited meanings to modern society. Every day, new technologies appear in the world to solve a particular problem. The speed at which technology influences life seems immeasurable. In doing so, technological advances spread across all professional fields, linking one area of ​​specialization to another. Initially, there were no direct links between applied sciences like biology and social sciences like political science. This is because the two fields deal with distinct and diverse ideologies. Nowadays, it seems that the two cannot function independently without each other. Somehow they intertwine on a similar application in the middle of an article......ss, Washington, DCGoulka, JE 2010, Towards a Comparison of DNA Profiling and Databases in the United States and England, RAND, Santa Monica, California. Grubb, A & Pearl, D 1990, Blood tests, AIDS and DNA profiling: law and policy, Family Law Press, Bristol. Harding, L 2007, databases DNA, Greenhaven Press, Detroit.Hindmarsh, RA & Prainsack, B 2010, Genetic suspects: global governance of forensic DNA profiling and databases, Cambridge University Press, Cambridge, MA.Lincoln, PJ & Thomson, J 1998, Forensic DNA Profiling Protocols, Humana Press, Totowa, NJ. Marzilli, A 2005, DNA Evidence, Chelsea House Publishers, Philadelphia, PA. Spencer, C 2004, Genetic testimony: a guide to forensic DNA profiling, Pearson/Prentice Hall, Upper Saddle River, NJ. Zeisel, H & Kaye, D 1997, Prove it with Numbers, Empirical Methods in Law and Litigation, Springer, New York, NY.