SummaryBioinformatics and Knowledge Management Systems (KMS) themselves are very broad and complex topics. The combination of the two topics creates a very specific but still open topic. Many other people have discussed KMS in specific subfields of the bioinformatics field, but none talk in detail about bioinformatics KMS (BKMS) as a whole. In this article, I will evaluate KMS based on my research and reviews in hopes of building a better KMS with specific tools so that I can not only present a good idea of ​​the topic, but also propose new ideas. The purpose of this is to talk about the USD Bioinformatics team and how this area has been researched, developed and, in the future, implemented in our own system. With these goals in mind, this team hopes to make a greater impact by integrating a good BKMS into their website.1.0 IntroductionThe topic of Bioinformatics and Knowledge Management (KM) and KMS is becoming increasingly popular over time. The rise of bioinformatics results from the influx of available genetic information (Luscombe, Greenbaum, & Gerstein, 2001). With this large amount of biological data, scientists needed to be able to manage this data for organization and retrieval purposes. With the rise of bioinformatics, we are at the same time witnessing the rise of knowledge management systems (Gallupe, 2000) and we can deduce that they are linked. This gave rise to what we know today as BKMS, a bioinformatics knowledge management system. Since BKMS is not a very popular topic, it is somewhat difficult to find a large amount of research on it. When you try to find out details about KMS in Bioinformatics or KM Bioinformatics or something similar, most of the time it's...... middle of article......eying the Landscape, (October), 1-27. Gold, AH, Malhotra, A. and Segars, AH (2001). Knowledge management: an organizational capabilities perspective. Journal of Management Information Systems, 18(1), 185-214. Jong, T. de and Ferguson-Hessler, MGM (1996). Types and qualities of knowledge. Educational Psychologist, 31(2), 105-113. Jung, J., Choi, I., and Song, M. (2007). An integration architecture for knowledge management systems and business process management systems. Computers in Industry, 58(1), 21-34. doi:10.1016/j.compind.2006.03.001Luscombe, N.M., Greenbaum, D., & Gerstein, M. (2001). What is bioinformatics? A proposed definition and overview of the field. Information Methods in Medicine, 40(4), 346-58. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11552348 Zack, M. H. (1999). Manage codified knowledge. Sloan Management Review, 40(4), 45–58.