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Essay / Hypertension in obese - 829
But in our study, obese with a parental history of hypertension showed a statistically significant increase in diastolic blood pressure and MAP compared to the other two groups, probably due to An overactive sympathetic nervous system as increased adiposity is significantly associated with increased sympathetic tone. 12 Increased SNS activity leads to increased peripheral vasoconstriction, leading to increased peripheral vascular resistance with increased diastolic blood pressure. Although several studies have shown a normal range of blood pressure in hypertensive children, 13 some studies have reported increased diastolic blood pressure in hypertensive children.14 In our study, the total HRV spectrum power was significantly reduced in hypertensive children. obese and non-obese children. normotensives with a parental history of hypertension compared to controls. Total power mainly reflects vagal power in modulating cardiovascular activity. 8 As total power is significantly reduced in obese and nonobese normotensives with a parental history of hypertension, this suggests suppression of vagal drive in hypertensive offspring. Our study showed decreased HF power in offspring with a parental history of hypertension. This decrease is apparent when HF power is expressed both in absolute values and in normalized units, because normalization tends to minimize the effect of changes in total power on the values of both HFs. In reality, the HF component is a quantitative expression of cardiac vagal control. This study clearly suggests that there was a profound parasympathetic impairment, primarily a reduction in vagal drive in offspring with a parental history of hypertension. A report by Surekharani et al also revealed...... middle of article ...... the siological process attributable to the VLF component is still unknown. In our study, we observed an increase in the LF/HF ratio in obese people. and non-obese subjects with a parental history of hypertension compared to subjects without a parental history of hypertension. A study of healthy obese and non-obese young Indian adults found that the LF and LF/HF ratio which measures sympathovagal balance in relation to the heart was increased in the obese, reflecting an increase in sympathetic drive.7 The report LF-HF is a most sensitive measure of sympathovagal balance. An increase in the LF-HF ratio indicates a sympathovagal imbalance, with increased sympathetic activity and decreased parasympathetic activity. In our study, we found higher values of the LF-HF ratio in obese individuals with a parental history of hypertension, indicating a more sympathetic cardiovascular system with depressed parasympathetic activity..