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Essay / Sun exposure, hives and risk of melanoma in Botswana: a case-control study
Malignant melanoma is skin cancer in which melanocytes transform into malignant cells. It accounts for about 4% of all skin cancers, but it is responsible for 80% of cancer-related deaths in the United States. Malignant melanoma is the 6th most common cancer among women and the 5th most common among men in the United States of America. It is usually detected or diagnosed in the adult stage with the median age at diagnosis being 58 years and only 0.9% of cases before the age of 20. (1).Say no to plagiarism. Get a tailor-made essay on “Why Violent Video Games Should Not Be Banned”? Get the original essay Its incidence increased rapidly in the 1970s, by about 6% per year. The annual increase in incidence is estimated to be approximately 3-7%. The increase in incidence rate has been attributed to screening and early detection of malignant melanoma and awareness (2). This type of skin cancer is more common in the Caucasian population than in Black people. Fair-skinned people are at increased risk of developing melanoma, approximately 17 to 25 times (1). Melanoma is reported to be more extremely rare than in blacks and most cases were of the acral lentiginous subtype (3, 4). Africans tend to be protected from the carcinogenic effects of UV rays than Caucasians due to higher levels of melanin. The most common sites where acral lentiginous melanomas develop in Africans and African Americans are the nail beds, soles of the feet, and palms. A retrospective analysis of melanoma in South Africans of mixed ancestry showed a histological type and anatomical distribution characteristic of black populations, but the 5-year survival rate in these patients was similar to that observed in white populations ( 5 ). The annual increase in the incidence rate of melanoma has been estimated at 3 to 7% per year among Caucasians (6). In most cases, malignant melanoma is diagnosed at stage 3 or higher, with a median survival of 6 to 9 months and a survival of 5 years. rate less than 5% (7, 8). Keep in mind: this is just a sample. Get a personalized article from our expert writers now. Get a personalized essay. The main predisposing factors are family history, exposure to UV rays, intermittent or chronic exposure, fair skin, history of melanoma. In a study carried out by Radespiel-Tröger, M. et al. confirmed that there is an increased risk of melanoma among outdoor workers (9). Outdoor workers had more risky behaviors with similar constitutional risk factors for skin cancer: more UV exposure (both occupational and recreational) and less sunscreen use and less health knowledge). This leads to higher exposure, more photo damage, and an increased risk of developing basal cell carcinoma and squamous cell carcinoma (10). High levels of sun exposure may be associated with skin cancers in people working outdoors, as well as insufficient use and practice of sun protection measures when working outdoors(11 ). A large number of people are exposed to varying levels of solar radiation at their workplace. In a study using the CAREX (Carcinogen Exposure) database designed to provide selected exposure data and documented estimates of the number of workers exposed to carcinogens by country, the most common occupational exposure to carcinogens in countries of the EU was the. (12).