Every year, antibiotic-resistant bacteria threaten more and more people. As problematic as it is, many people are unaware of the term drug resistance. Since it is a growing concern, it becomes confusing as to why drug resistance arises and what steps can be taken to prevent it. Because drug resistance is a real health problem, determining what it is, how these bacteria can acquire antimicrobial agents, and possible solutions to resistance are the types of actions that must be taken in order to better understand How powerful are these drug-resistant bacteria? Drug resistance is the ability of a microbe, such as a bacteria, to continue to grow even in the presence of an antimicrobial, which is intended to stop growth or kill the microbe. In this particular case, the antimicrobial becomes unusable when attempting to treat or cure a specific infection. As a result, the drug becomes ineffective due to the resistance that the microbe has developed towards it. The reason this happens is due to a gene that certain microbes have that allows them to become resistant to antimicrobials. Bacteria can develop this resistance through mutations as well as when they obtain a new DNA helicase. When there is a mutated bacteria, the antimicrobial often has difficulty recognizing the genetic material of the bacteria. That being said, if the antimicrobial does not have a chance to locate the binding site on bacterial DNA, the drug will not have a chance to work. Fluroquinolones are a perfect example of how bacteria can develop resistance through resistance. Fluroquinolones cannot bind to the enzymes DNA gyrase and topoisomerase if these enzymes are mutated in the case of the antibiotic known as vancomycin. In order to treat this vicious bacteria, the drug vancomycin was introduced in hopes of providing treatment for the infection. However, a gene resistant to this drug eventually emerged and began spreading in hospitals. “These strains, known as vancomycin-resistant S. aureus (VRSA), are descendants of MRSA that have acquired a set of five genes that travel together as a “cassette” and confer vancomycin” (Walsh and Fishbach , 2009). Unfortunately, the enzyme located in the resistant gene of the bacteria allows the target to be modified, which does not allow vancomycin to bind. Obviously, MRSA and VRSA pose a huge dilemma, because both bacteria can spread quite easily and the resistant gene is so strong that even drugs that would be considered "last resort" develop problems when trying to treat them..