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  • Essay / Antioxidant Efficacy of Bryophyllum Pinnatum (katakataka) and Wound Healing Capabilities Used in the Treatment of Wound Burns

    Table of ContentsReview of Related LiteratureKatakataka PlantAntimicrobial PropertiesIntroductionWound burn is described as damage to the skin or to other natural tissue caused by heat or radiation, radioactivity, power, friction or contact with chemicals. It is considered a global public health problem because each year, the approximate number of deaths caused and generated by burns amounts to 180,000 (World Health Organization [WHO], 2018). According to Elloso and Cruz (2017), the Philippines has a total of 4 burn centers that treat approximately 300 to 400 burn cases per year. There is therefore a need for an effective, alternative and easily accessible treatment for wound burns. Determining the properties of medicinal plants used in the treatment of wound burns can be developed into a more effective wound burn medicine that can help future Filipino patients in the treatment of wound burns. Say no to plagiarism. Get a tailor-made essay on “Why violent video games should not be banned”?Get an original essayIn the study by Obiama, Chikanka, and Dumo (2017), it is mentioned that there are various medicinal plants that can help to treat wounds. burn. One of them is Bryophyllum pinnatum or also known as Katakataka in the Philippines. It is an herbaceous plant from the Crassulcea family which is frequently used to treat or cure urinary stones, hypertension, colds, abscesses, asthma, insect bites, skin disorders and other diseases. Bryophyllum pinnatum (Katakataka) can be used in many ways, including the leaves of the said plant. Its leaves contain astringent, antiseptic, antimicrobial, antibacterial, healing and many other properties. It can be used to treat wound burns, sprains, eczema, infections, carbuncles and erysipelas by pounding fresh material to apply as a poultice for various conditions (Stuart, 2017). Different extracts of Bryophyllum pinnatum (Katakataka) are applied to treat different diseases, especially wound burns. However, most previous researchers who performed the experiment performed it using another compound. A previous study titled “Anti-inflammatory effects of Bryophyllum pinnatum (Lam.) Oken ethanol extract in acute and chronic skin inflammation” investigated the anti-inflammatory abilities in relation to acute and chronic skin treatment. Nevertheless, the study did not discuss or mention anything about wound healing activities. They also did not follow the procedure they developed which involves using only the extracts of the plant Bryophyllum pinnatum (Katakataka), their experiment was supported by other components as mentioned above. The objective of the study is to determine whether the wound healing capabilities of Bryophyllum pinnatum (Katakataka) can serve as a treatment for wound burns. The study aims to identify the antioxidant properties of different extracts of Bryophyllum pinnatum (Katakataka) using (Which method would DOST suggest). It also aims to prove that Bryophyllum pinnatum (Katakataka) alone has antioxidant and healing capabilities. This study will help future researchers gain additional knowledge about the antibacterial components of Bryophyllum pinnatum (Katakataka). Researchers will also focus on modifying previous studies investigatingthe disease and on the same plant used. Furthermore, this study will have a great impact in providing new concepts and ideas regarding the manipulation of Bryophyllum pinnatum (Katakataka) that can be used to treat or reduce the number of people suffering from any disease, illness or disease. a particular condition. This research is especially important for those who have burns, because the result of the observation of Bryophyllum pinnatum (Katakataka) can be used as an alternative treatment. Researchers mainly focused on the use of Bryophyllum pinnatum (Katakataka) and confirming the effectiveness of its antioxidant and healing properties. This study also concerns the validity of Bryophyllum pinnatum (Katakataka) extracts for healing wound burns without the aid of other constituents. Additionally, the only limitation of the study is that testing will be performed only on specific areas such as antioxidants and wound healing properties as well as Bryophyllum Pinnatum (Katakataka) extracts, due to the limited time and financial sources. The study would most likely address concerns about wound burning and the plant's capabilities. Review of Related Literature Katakataka Plant The use of medicinal plants is growing worldwide due to the increasing toxicity and allergic manifestations of artificial and synthetic drugs. The plant, Bryophyllum pinnatum (Crassulaceae) or Kalanchoe pinnata, well known in the Philippines as Katakataka, is considered a miracle plant accepted as an herbal remedy in almost all parts of the world (Lunkad, Angrawal & Kothawade, 2016 ). ). It is defined as a widely distributed perennial medicinal plant (Aprioku and Igbe, 2017). On the other hand, Stuart (2017) characterized it as an erect, smooth, juicy grass commonly found in tropical regions. For example, the countries of India, Africa, Madagascar and the Philippines where they mainly use it as medicine to cure diseases (Lunkad, Angrawal & Kothawade, 2016). Bryophyllum pinnatum (Katakataka) is also described as a plant with elliptical leaflets that typically grow up to 10 cm long with thick, succulent, scalloped margins (Stuart, 2017). Furthermore, Jason (2017) also described that Bryophyllum pinnatum (Katakataka) is a fast growing plant that grows simply by its leaves and is easy to maintain as it does not require daily watering. Based on Balinado and Chan (2017), documentation of ethnomedical knowledge and practices in a local district is carried out to help dictate the importance and variety of traditional medicinal uses. The study covers about seventy-six (76) medicinal plants belonging to almost 40 families represented mainly by Lamiaceae and most of these plants are cultivated herbs and shrubs whose leaves were generally harvested for their useful extracts. There are around twelve categories of several conditions that follow the International Classification of Diseases (ICD-10), and these conditions are said to be cured by Bryophyllum pinnatum (Katakataka plant). Through quantitative analyses, researchers discovered the most popular species for different categories of diseases, Bryophyllum pinnatum (Katakataka plant) is one of them. The study also showed the importance of the wide variety of plant species on the knowledge and practices of citizens. These plants like Bryophyllum pinnatum (Katakataka plant) play an important role in maintaining local healthcare despite all the modernization happening in today's world. The study stated that theMedicinal plants could be further analyzed to verify their safety and effectiveness for local and future scientific and pharmaceutical applications. According to the research of Lunkad, Angrawal, and Kothawade (2016), Bryophyllum pinnatum (Katakataka) is commonly known for its healing properties and has been used for generations in the field of medicine. In other parts of the world, Bryophyllum pinnatum (Katakataka) is also called plant of life or miracle leaf because the whole plant can be used as a medicinal plant. Studies have shown that Bryophyllum pinnatum (Katakataka) has the ability to cure diarrhea, headaches and asthma; It is proven to treat wounds, bruises, or burns simply by applying the extract of the plant (Jason, 2017). Additionally, Aprioku and Igbe (2017) claimed that Bryophyllum pinnatum has healing properties and could treat microbial infections, skin ulcers, rheumatism, heartburn and other diseases. These benefits can be acquired from the leaves of Bryophyllum pinnatum (Katakataka) as they are known for their antibacterial, antiseptic, disinfectant and many other properties (Stuart, 2017). Antimicrobial propertiesAccording to the Journal of Antimicrobial Agents (nd), an antimicrobial is a specialist that slows down the development of microorganisms. The microbial specialist can be chemical substance and physical operators. These operators are involved in the development and propagation of responsible living beings such as bacteria, fungi, parasites, infections, etc. A microorganism or organism is a living life form that is too small to see with the naked eye but perceptible under a magnifying glass. Microbiology is the study of microorganisms. Microscopic organisms such as bacteria, fungi, archaea or protists are incorporated under microorganisms. Antibacterial is an operator that interferes with the development and spread of microbes. These agents eradicate or neutralize microscopic organisms by fighting against bacterial compounds. Hot synthetic compounds, for example, chlorine, and all antimicrobial drugs have antibacterial properties. Antimicrobial drugs are used to treat microbial disease. Antimicrobial drugs can be collected by the microorganisms against which they basically act. Modifies anti-infective agents, antifungals, antiprotozoal and antiviral drugs. Additionally, according to Medicine Net. (nd). Antimicrobial is a general term given to substances, especially drugs, that cause or moderate the development of organisms. Microbe is a global name given to microorganisms like Staphylococcus aureus, which causes some staph infections, infections (e.g., influenza, which causes this season's flu virus), fungi (e.g., Candida albicans, which causes contamination by yeasts) and parasites (for example, Plasmodium falciparum, responsible for jungle fever or malaria). Specialist models of antimicrobials are tetracycline (an anti-infective used to treat urinary tract diseases), Oseltamivir or Tamiflu (an antiviral that treats influenza), and Terbinafine or Lamisil (an antifungal that can cure athlete's foot). An anti-infective or antibiotic is a medication intended to execute or moderate the growth of microorganisms and some organisms. Antibiotics are regularly used to fight bacterial diseases, but cannot fight contamination caused by infections. Antibacterial is the term given to substances.