Table of contentsIntroductionThe stages of Alzheimer's diseaseRisk factor for Alzheimer's diseaseDiagnosis of Alzheimer's diseaseConclusionAlzheimer's disease is a disease of intelligence in which the cells of our understanding break down to connect all the others. patient because because more rubbery, twisted proteins are available between the intellectual cells, so the cells fail to convey the message. This disease appears gradually at an early stage, the doctor cannot diagnose the disease. Almost in the fourth sage, this disease was completely diagnosed. In this disease, the patient becomes unconscious of his surroundings. Stress, high sugar levels, obesity, heredity and lack of education are major factors in Alzheimer's disease. Nowadays, many people are suffering from this disease, but there is no specific diagnosis of this disease, but some tests like PET, CT, MMSE and MRI can diagnose. Certain lab and blood tests can also diagnose it. There is no treatment for Alzheimer's disease, but some medications like cholinesterase and nemantine are used for the treatment of this disease. Certain nutrients and regular physical activity also play an important role in the treatment of Alzheimer's disease. Say no to plagiarism. Get a tailor-made essay on “Why Violent Video Games Should Not Be Banned”? Get the original essayTagsAlzheimer's disease, patients, depression, plaques and tanglesIntroductionAlzheimer's disease is a mental illness in which the fall of a section suggests itself which origin memory defeat, obstacle decision the complete word, the changes of mood, persist in perplexity once the ordinary errands and the mind are repetitive. Alzheimer's disease is the daily cause of dementia, a set of common sense disorders that underlie the deficit of intellectual and collective skills in frequent elderly people. In the field of intelligence, he questions the plaques and entanglements that incite memorial defeat. (Ahmed A et al 2013) the doctor Alois Alzheimer discovered an advertisement while he was examining at length a serene woman Auguste D, who was suffering from a health problem, nap disorders, memory turbulence, aggressiveness , crying and progressive confusion. (Reger B 2002). It has established dense deposits around its nerve cells. Alzheimer, who was a German neurologist and psychiatrist, noticed abnormal deposits in a 51-year-old former woman with dementia. It has been established that patients with Alzheimer's disease often have common-sense abnormalities called plaques and tangles. (Hippius H and Neundörfer G, 2003). Plaques and tangles called beta-amyloid and tau interrupt the transfer between nerve cells and the intellect. fractional mutilation as a result, the mind is able to not function as habitual behavior such as thinking, eating, sitting, speaking and other functions that the container does not usually perform. (Morae AHC et al, 2013) At present, more than 25 million people are in misery in Alzheimer's disease on earth and 4.6 million countries increase all year round (Ahmed A et al 2013 ). Pakistan is a booming country, it is estimated that by 2050, Pakistan will become the third most densely populated country in the world (Khan Q, 2017). In Pakistan, we hope to experience that the rate of Alzheimer's disease is too better. In neighboring Pakistan, there is no specific record of designated Alzheimer's diseaseto lack exploration and life if you have this condition due to lack of awareness. .To overcome this disease, some influential steps can be taken. (Seetlani NK, 2016). The individual who suffers from Alzheimer's disease gives rise to extremely large plaques and tangles. Plaques are the clumps of proteins that are born. The gap between faction and tangles is any twisted protein that appears inside cells (Farley P, 2013). When a self gets older at that point, the concentration of plaques and tangles is better. They deter the transfer between nervous compartments and in response they trigger the defeat of memories, the problem of acting on daily behavior and others (Hardy J 2006) the understanding is calm of 100 billion nerve cabins and each nerve cabin is joined a new nerve cabal for email, for belief and training around other functions as soon as these plaques and tangles fill up, they dent the nerve chamber, these mutilations occur in the hippocampus in reasoned work that is responsible for accepted wisdom and causes Alzheimer's disease. (Agdeppa ED, Kepe V, Liu j et al 2001). Stages of Alzheimer's disease. In this case, a character remains practically average and shows no symptoms of Alzheimer's disease. No healthcare profession has symptoms of Alzheimer's disease. phase the human being is implemented in daily life. For the stage, any gathering of the day, they do not need the help of another person. (Albert M 1994). In the case of mild and exact cognitive decline, the tables around approximately few symptoms appear and during this period, common mood changes appear, but a furthermore comprehensive corrective examination does not reveal that the person People with Alzheimer's disease suffer from short-term memory loss, like when they talk to others, they forget some words of what they want to say to others and they also forget where they kept something. But at this point, over time, they remember all the things and remain normal, perform their function normally. at this stage this disease has not been diagnosed. People with early Alzheimer's disease may have difficulty performing functions such as planning, organizational skills to solve a problem and manage a difficult situation, but they remain independent of others and do not need to help others (Albert MS, Heller HS, Milberg W. 1988). This is an early stage of diagnosis in which Alzheimer's disease can be detected, but it is a difficult stage to detect. At this stage, symptoms may appear, but Alzheimer's disease is not diagnosed in all patients but only in some. patients (Shahmiri, E. et al 2017). Alzheimer's disease can be detected. At this stage, the problem of memory loss arises, without judging anything (Wattmo C et al 2016). When a person reads something, he forgets what I read, he repeats the same question over and over again. The person faces many difficulties while making a plan. and sometimes they forget their own name when in front of new people or in a meeting because they are confused and do not face new people. And at this point, family members and friends may notice all these things. At this stage, the doctor can detect Alzheimer's disease, PET scan and other tests can detect Alzheimer's disease. (Albert M. 1994). This is a mild or early stage of Alzheimer's disease. At this stage, a person exhibits signs and symptomsclear signs of Alzheimer's disease because at this stage everyone can notice the signs and symptoms and at this stage Alzheimer's disease can easily be detected by the PET test. At this stage, a person is afraid of whether or not society will select them into this environment (fear of rejection), a lack of responsiveness to which they cannot respond. any problem, loss of intellectual ability in which they cannot solve simple questions or answer simple questions (Albert M 1994). They experience difficulty when performing normal or daily tasks, and also they sometimes forget their own history and they don't know who is he, what is his name? All these symptoms appear at this stage, they face a lot of problems in their life and The doctor easily detects Alzheimer's disease at this stage. (Wattmo C et al 2016) This is an intermediate stage of Alzheimer's disease. A person may no longer be able to carry out normal daily activities such as dressing or bathing. At this point, a person has become confused, not knowing where they are and what day it is?. She should help others choose how to dress according to the season (Tarawneh R and Holtzman DM, 2012). The person further suffers from problems with loss of memory, mental activity and also loses the ability to solve any problem they are not able to solve any problem and cannot perform their daily tasks. In all areas of life, they face problems because they do not show normal behavior. (Suthers K, 2003) This is severe or advanced Alzheimer's disease. At this stage, the person is completely unable to react to their environment as it is the last stage of Alzheimer's disease. The person needs help to respond to environmental changes and also needs help to perform daily activities such as eating, drinking and sitting, etc. She may lose the ability to speak, walk or smile without help. She needs care from a nurse who helps her. patients eat, drink and sit. They lose the ability to speak their sentence or briefly explain any problem in one word. These steps are very serious steps for this person. (Tarawneh R and Holtzman DM, 2012). Risk Factor for Alzheimer's Disease There are many factors that cause Alzheimer's disease, such as a history of diabetes, depression, smoking, obesity, family history, and less education. Chen ST et al (2014). Type II diabetes is the main dynamic consequence of Alzheimer's disease because it leads to a stock of Aβ in the intellectual compartment and is not able to use insulin in quantity or insulin is not not suitable if one quality is overweight every time. These situations occur (Alford S et al 2017) and the cells do not return to insulin, so the glucose largely goes to multiply, which leads to an increase in blood pressure and ultimately triggers Alzheimer's disease. Alzheimer’s. (Sultana N, 2011) Smoking is too motivated. diabetes and countless other diseases such as cancer, cardiovascular diseases (Anstey kj, 2007). Smokers have a 45% chance of developing dementia compared to non-smokers. Ex-smokers (a big cheese who knew how to quit smoking) know how to reduce the consequences of Alzheimer's disease by not smoking. Cigarette smoke/smoking is linked to billboard neuropathology in preclinical models and in humans. (Durazzo.CT 2014) Cigarette smoke tolerates pollutants that promote oxidative stress and inflammation, which are also linked to increased diseaseof Alzheimer's. The human being who pant the cigarette, his internal system also wakes up and these also have a chance to trigger Alzheimer's disease (Anstey KJ, 2007). Depression caused 20 to 40% of associates affected by Alzheimer's disease. Higher risk of depression originates in women rather than men, therefore women are more affected by Alzheimer's disease. Events that cause depression, such as lack of social support in which society can support the person, stressful life events, such as economic stress, in which they do not receive sufficient salary to fulfill their desire, isolation and loneliness. These are all reasons that cause depression and ultimately affect Alzheimer's disease. (Usman S et al 2010). Depression produces understanding of a group that is older and at additional risk of developing Alzheimer's disease. (Ownby R L. et al. 2006). Obesity or overweight is also a risk factor for Alzheimer's disease because obesity or overweight causes increased blood pressure and increased blood pressure causes Alzheimer's disease. A higher body mass index measures obesity and overweight in people. .when a person is obese or overweight, then they have higher blood pressure and are more likely to develop diabetes and we know that diabetes causes Alzheimer's disease. (Usman S et al, 2010). Parents contain apolipoprotein on DNA, totaling 9. have two contours ApoE -e2 and ApoE_e3 mutually, parents pass one DNA to offspring if metamorphosis is correct, one parent transfers both DNA to the offspring, after which they affect Alzheimer's disease. Apolipoprotein E is a set of proteins captured in the metabolism of fats in the lion's share (Roses AD, 1996). ApoE is a driver of cholesterol and fat in the understanding at that point that cholesterol and fat accumulate side by side in the federation of chubby or heaviness caused, thereforeit is in this mode that they are at the origin of Alzheimer's disease. The qualities that APOE-e4 RNA possesses give rise to an additional challenge for cultivating Alzheimer's disease compared to individuals who do not completely possess this gene. (Caselli, JR 2013). Less education is also a risk factor for Alzheimer's disease. Most of the time, they run the risk of are seen in less educated people (Sharp ES and Gatz M 2011) who are not aware of this disease and. People who are mentally functioning are not diagnosed with Alzheimer's disease compared to people who are not mentally active. a pancake creates a synaptic connection in the intellect and participates in key work in the formation of memory. These associations enter a neural network like one neuron connects to an alternative neuron. If this disease progresses in the corpse, neuronal damage occurs. (Usman S et al 2010). Diagnosis of Alzheimer's disease. Alzheimer's disease can be diagnosed through family interviews, knowing the patient's history, physical examinations of the patient, and certain neuroimaging tests. Measurement of biomarkers also play an important role in the diagnosis of Alzheimer's disease. (Feldman HH et al,2008).Influence/role of biomarkersBiomarkers play an important role as an indicator in the measurement and evaluation of biological process and pharmacological responses. (Colburn et al., 2000). Biomarkers also play an important role in the diagnosis of Alzheimer's disease. (Blennow, 2010)Neuropsychological tests: Neuropsychological tests used for.