What are Hijras? Are they men or women? Hijras believe that they are neither male nor female (Patel, 2010). Hijras struggle with their social status, some are accepted and others excluded, it depends on the location (Patel, 2010). Due to the struggle for social status, some Hijras engage in sex work, which brings HIV and sexually transmitted infections into play. According to Abdullah, Hijras are a major source of spread of various STIs (Abdullah et al., 2012). In 1999, there were between 2.5 and three million people living with HIV or AIDS in India (Patel, 2010). In this context, the prevalence of HIV or AIDS among Hijras was higher than that of other men who have sex with men (Patel, 2010). It is a global health problem; the spread of HIV or AIDS within the Hegira is significant (Patel, 2010). This article will argue that due to Hijras' difficulties with their social status, they are at higher risk of contracting HIV or AIDS and they are at higher risk of spreading it. Hijras are born male, but identify as female (Patel, 2010). . They adopt women’s clothing and mannerisms (Patel, 2010). Hijras are known as “gender intersex” because they do not identify as either men or women (Patel, 2010). Many Hijras feel incomplete and claim to have “a woman's soul imprisoned in a man's body” (Abdullah, et al., 2012). Some Hijras choose to physically complete their “spiritual connection with the female form through a ritualized castration process called “nivan”” (Patel, 2010). Those who retain their male genitalia nevertheless abandon their masculine sexuality (Patel, 2010). Punjabi ethnographers of the early 20th century noted that Hijras described themselves as helpless (Lal, 1999). Many Hijras are Zananapan, who are middle of paper......, N., Hassan, Z., Jan, A., et al. (2012). Is social exclusion pushing Pakistani Hijras (transgenders) into the sex trade? A qualitative study. BMC International Health and Human Rights, 12, 1-9. Altaf, A., Zahidie, A. and Agha, A. (2012). Comparison of HIV risk factors among Hijra sex workers in Larkana and other cities of Pakistan: a cross-sectional analytical study. BMC Public Health, 12, 279. Khan, A., Rehan, N., Qayyum, K. and Khan, A. (2008). Correlates and prevalence of HIV and sexually transmitted infections among Hijras (transgender males) in Pakistan. International Journal of STDs and AIDS, 19, 817-820.Lal, V. (1999). Not this, not that India's Hijras and the cultural politics of sexuality. Social Text, 17 (4), 119.Patel, A. (2010). Hijras in India: the case for transgender rights. George Washington Review of International Law , 42 (4), 835-863.