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  • Essay / Hemodialysis Review

    Hemodialysis is a method of removing impurities such as creatinine, phosphorus, potassium and urea, as well as free water from the blood in cases of kidney failure . If the patient is suffering from kidney dysfunction, the impurities are removed using artificial means of a machine called hemodialysis. The dialysis procedure is very tedious and time-consuming for patients. Patients need to visit the hospital frequently 1 to 4 times a week depending on the condition of their kidneys. The patient's blood is removed from the radial artery and then sent to the dialyzer to be filtered. Filtered blood is returned to the body through the femoral artery. The dialysis procedure carries its own risks and limitations, such as fatigue, anemia, emboli formation and the risk of infections. These disadvantages can be overcome by using a portable renal dialyzer (WKD), which is a miniature form of dialyzer. This can be worn as a belt around the patient's waist. The portable kidney dialyzer contains a pump system that draws blood in and out of the body, a dialysis unit, a temperature monitor, a pH meter, a flow sensor, a battery and a solar panel for additional power supply . The portable artificial kidney works using batteries and a solar panel for electricity generation. The portable kidney dialyzer can be worn continuously and will perform the function of a natural kidney. The filtration rate is 12 ml/min synchronously. The advantage of the proposed method is a slow and continuous process that can avoid fatigue and other complications. The patient does not need to waste his precious time, he can move around even during the dialysis procedure. The mobile application is developed to monitor all clinical parameters of the patient using the Android application to communicate with the doctor remotely. Say no to plagiarism. Get a tailor-made essay on “Why violent video games should not be banned”?Get the original essay India has a population of 1.2 billion and has seen good economic improvement in recent years. Globalization and urbanization have radically changed eating habits and lifestyle habits. This has become the cause of a rapid increase in lifestyle diseases such as diabetes, heart disease, hypertension and chronic kidney disease (CKD). Chronic kidney disease has now increased around the world, with global annual growth in the number of patients with ESRD (end-stage renal disease) of 7%. CKD is considered a significant cause of death in most countries, especially in economically backward countries due to high disease burden, expensive treatments, and lack of awareness about disease prevention. The burden of ESRD in India is estimated to be approximately 1,650,000 to 2,200,000 people each year out of a population of 1.2 billion. Among them, only 10% or less of patients receive renal replacement therapy [1]. Healthy kidneys filter impurities from the blood like excess fluid, minerals and waste. When the kidney is not functioning properly, harmful waste products build up in the blood, causing the body to retain more fluid and not produce enough red blood cells. This problem must be immediately treated by replacing the work of the failing kidney with organ transplantation or hemodialysis. Hemodialysis is a blood filtration procedure by extracting blood from the body and passing it through a special filter that removes waste, minerals and salts. Then the clean blood is returned to the body. Hemodialysis helps control theblood pressure and maintain a good chemical balance of the blood by filtering unwanted minerals and salt. One of the major disadvantages is that the patient receiving this treatment must follow a very strict diet and schedule. The procedure is performed 2 to 4 times a week depending on the severity and each session lasts up to 3 to 5 hours. Even when making every effort to adapt to the effects of kidney failure, patients often face difficulties in their professional and personal lives [2]. The patient must be restrained to the machine during the entire procedure. As the patient is attached to the machine 3-4 times a week for 3-5 hours in each session, the patient will definitely spend most of the time in the hospital, which will affect the quality of his lifestyle and prevent him from continue his daily life. To overcome this drawback, the idea of ​​developing a portable artificial kidney was taken up by Kolff (1970s) to improve the quality of life of patients by allowing them to move freely even during the intervention [3]. The wearable artificial kidney is a miniature dialysis machine designed in such a way that it can be worn around the waist like a tool belt [4]. There are different types of portable dialysis machines that are still in the research phase. This device can be worn and used by the patient up to 24 hours a day for a slow and gentle dialysis procedure, just like the natural kidney. It is the best way to mimic the biological functions of the kidneys and, thanks to its slow and continuous dialysis, blood pressure is kept under control and reduces the need for phosphate binders and anti-anemia medications. The wearable artificial kidney developed so far is still under research. and the development process. The biggest drawback is the power supply, which turns off in the middle of dialysis. Therefore, to overcome this problem, we have included a solar panel, which acts as a backup power supply, allowing the process to continue even when the battery runs out of power. An application is also developed to monitor parameters such as pressure, flow and any changes in the fluid structure. These parameters are transferred via Bluetooth to the mobile application which sends these values ​​​​to the doctor's phone via SMS. This will make it much easier for a remote doctor to monitor the patient. The solar panel provides the energy to run the device when the battery runs out, so dialysis doesn't stop in the middle. The wearable artificial kidney mimics natural kidney function with a slow, continuous filtering process. The entire device is attached to a belt so that the patient can move freely during the procedure. The device contains a special filter used to filter blood, a pump, a flow sensor, a pressure sensor, an IR sensor, an LED screen, a relay, a solar panel, a pH meter, a battery, Bluetooth and ARDUINO. ARDUINO: ARDUINO is a single board microcontroller used to make electronics more accessible in multidisciplinary projects. The hardware consists of a simple open source hardware board built around 8-bit Atmel AVR or 32-bit Atmel ARM. Software - consists of a standard programming language compiler and a bootload used to run the microcontroller. LCD DISPLAY: The LCD screen is made of liquid crystal material sandwiched between two transparent sheets of glass. LCD screens generally have a thin diameter, are lightweight and consume less power. They can therefore be used in low-power projects and can operate for a long time with less power consumption. It is generallyused in watches, calculators and other measuring instruments. RELAY: A relay is an electrically operated switch that typically uses an electromagnet to mechanically switch relays. But other principles like solid state relays are also used. Relays are used in the electrical circuit to protect them from heavy loads and faults. In modern electrical circuits, a digital instrument called a “protective relay” performs these functions. DC PUMP: A micro oil/water circulation pump is used to convey the liquid to be dialyzed in and out of the machine. It can be used continuously, withstands high fluid temperatures and has a low noise level. SOLAR PANEL: A solar panel consists of a group of solar cells capable of converting sunlight into electricity. Solar energy has a wide range of uses ranging from its use in watches, calculators, road lighting to powering buildings and solar aircraft. The cells are made of a semiconductor material, often silicone is used. There are 2 layers of silicone in a solar cell: type N and type P. Electricity is produced by light entering the cell, the silicon absorbs part of the light. The energy from light causes electrons to flow out of atoms, producing electricity through the flow of electrons between two layers. Electricity can leave the cell through metal contact wires. FLOW SENSOR: The flow sensor has a small rotating fan enclosed in a chamber that rotates when fluid passes through the sensor. We measure the rotation speed, which is directly proportional to the flow rate of the fluid. Blood flow is kept slow and steady to promote an efficient filtration process. DIALYSER CHAMBER: The dialyzer chamber is the part where the actual filtration process takes place. The chamber contains a bundle of hair resembling fine hollow fibers. Blood flows inside these fibers in one direction and dialysate fluid flows outside these fibers into the chamber. This opposite flow direction and the concentration gradient between the blood and the dialysate fluid enable the filtration process. The hollow fibers act as a semi-permeable membrane and minerals, urea and phosphate from the blood move into the dialysate fluid due to the concentration gradient. RESORBENT CHAMBER: The dialysate fluid is contaminated with all the toxins and minerals that have passed from the blood to the bloodstream. fluid. It must therefore be purified before entering the dialyzer chamber to filter the blood. This chamber contains activated carbon which absorbs minerals and toxins from the dialysate fluid as it passes through the chamber. Thus, pure dialysate liquid is supplied to the dialysis chamber every time.BLUETOOTH AND MOBILE APPLICATION: Sensor parameters such as flow rate and pressure displayed on the LCD screen are also sent to a mobile application via Bluetooth. These values ​​are then sent to a doctor's phone via SMS. This allows the hospital doctor to monitor the patient at home so that the patient does not have to visit the hospital unnecessarily. A blood substitute is used instead of blood, which has a very close similarity to natural body fluids. The dialysate fluid used is a mixture of sterile water with bicarbonate salts and sodium chloride. The blood substitute is pumped into the dialysis chamber, where filtration takes place. Fluid flow and pressure are measured using the sensors. The pH is measured before and after filtration to ensure that purification has been carried out. Power supplied comes from a 9V battery and a.